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Tg(Prnp-App/APPswe)E1-2Dbo
Transgene Detail
Nomenclature
Symbol: Tg(Prnp-App/APPswe)E1-2Dbo
Name: transgene insertion E1-2, David R Borchelt
MGI ID: MGI:3696473
Synonyms: E1-2 line, line E1-2, Mo/Hu APPswe, Mo/Hu APPswe line E1-2
Transgene: Tg(Prnp-App/APPswe)E1-2Dbo  Location: unknown  
Transgene
origin
Strain of Origin:  (C57BL/6J x C3H/HeJ)F2
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Mutation details
Phenotypes
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Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Notes
Three transgenic lines were generated and designated by the authors lines Q2-2, E1-2 and C3-3 (Tg(APP695)3Dbo). They were estimated, on the basis of Southern blot analysis, to carry 3-10 copies of the transgene.

References
Original:  J:80782 Borchelt DR, et al., A vector for expressing foreign genes in the brains and hearts of transgenic mice. Genet Anal. 1996 Dec;13(6):159-63
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory