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Bcl3tm1Rsch
Targeted Allele Detail
Nomenclature
Symbol: Bcl3tm1Rsch
Name: B cell leukemia/lymphoma 3; targeted mutation 1, Roland M Schmid
MGI ID: MGI:3695737
Synonyms: Bcl-3-
Gene: Bcl3  Location: Chr7:19808462-19822770 bp, - strand  Genetic Position: Chr7, 9.95 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:116724
Parent Cell Line:  E14.1 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA neomycin resistance cassette replaced a fragment of the locus encoding the ankyrin repeat sequences 1-4. (J:116724)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Bcl3 Mutation:  37 strains or lines available
References
Original:  J:116724 Riemann M, et al., The IkappaB protein Bcl-3 negatively regulates transcription of the IL-10 gene in macrophages. J Immunol. 2005 Sep 15;175(6):3560-8
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/22/2016
MGI 6.06
The Jackson Laboratory