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Unc13atm3Bros
Targeted Allele Detail
Nomenclature
Symbol: Unc13atm3Bros
Name: unc-13 homolog A; targeted mutation 3, Nils Brose
MGI ID: MGI:3695486
Synonyms: m, Munc13-1-EYFP
Gene: Unc13a  Location: Chr8:71626712-71671775 bp, - strand  Genetic Position: Chr8, 34.43 cM, cytoband B3.3
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:116766
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion
 
Mutation detailsThe STOP codon in exon 45 was replaced with EYFP cDNA in-frame. Western blot confirmed expression of the mutant protein. (J:116766)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Unc13a Mutation:  43 strains or lines available
References
Original:  J:116766 Kalla S, et al., Molecular dynamics of a presynaptic active zone protein studied in Munc13-1-enhanced yellow fluorescent protein knock-in mutant mice. J Neurosci. 2006 Dec 13;26(50):13054-66
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
10/15/2019
MGI 6.14
The Jackson Laboratory