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Targeted Allele Detail
Symbol: Nasptm1Mgor
Name: nuclear autoantigenic sperm protein (histone-binding); targeted mutation 1, Michael G O'Rand
MGI ID: MGI:3694795
Synonyms: Nasp-
Gene: Nasp  Location: Chr4:116601052-116627941 bp, - strand  Genetic Position: Chr4, 53.24 cM, cytoband D1
Germline Transmission:  Earliest citation of germline transmission: J:116454
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsSix exons were removed from the locus, resulting in the loss of amino acid residues 100-605 in the tNASP sequence and amino acid residues 74-253 in the sNASP sequence. (J:116454)
View phenotypes for all genotypes (concatenated display).
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Nasp Mutation:  33 strains or lines available
Original:  J:116454 Richardson RT, et al., Nuclear autoantigenic sperm protein (NASP), a linker histone chaperone that is required for cell proliferation. J Biol Chem. 2006 Jul 28;281(30):21526-34
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.06
The Jackson Laboratory