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Amelxtm2Msnd
Targeted Allele Detail
Summary
Symbol: Amelxtm2Msnd
Name: amelogenin, X-linked; targeted mutation 2, Malcolm L Snead
MGI ID: MGI:3694787
Synonyms: deltaB
Gene: Amelx  Location: ChrX:167959110-167970196 bp, - strand  Genetic Position: ChrX, 78.95 cM
Alliance: Amelxtm2Msnd page
Enamel architecture changes in Amelxtm1Msnd/Amelxtm1Msnd and Amelxtm2Msnd/Amelxtm2Msnd mice

Show the 2 phenotype image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:116448
Parent Cell Line:  RW-4 (ES Cell)
Strain of Origin:  129X1/SvJ
Mutation
description
Allele Type:    Targeted (Inserted expressed sequence)
Mutation:    Insertion
 
Mutation detailsA targeting vector was designed to insert a minigene lacking a carboxyl-terminal conserved domain defined by residues 157-173. (J:116448)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Amelx Mutation:  25 strains or lines available
References
Original:  J:116448 Zhu D, et al., Altering biomineralization by protein design. J Biol Chem. 2006 Jul 28;281(30):21173-82
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory