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Hnrnpdtm1Rjsc
Targeted Allele Detail
Nomenclature
Symbol: Hnrnpdtm1Rjsc
Name: heterogeneous nuclear ribonucleoprotein D; targeted mutation 1, Robert J Schneider
MGI ID: MGI:3693617
Synonyms: Auf1-
Gene: Hnrnpd  Location: Chr5:99955935-99978938 bp, - strand  Genetic Position: Chr5, 48.46 cM, cytoband E3
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:116112
Parent Cell Line:  W4 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe 5' sequence of exon 3 was replaced with a neomycin resistance cassette. Immunoblot confirmed absence of protein in mutant spleen, thymus and testicle. (J:116112)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hnrnpd Mutation:  10 strains or lines available
References
Original:  J:116112 Lu JY, et al., Endotoxic shock in AUF1 knockout mice mediated by failure to degrade proinflammatory cytokine mRNAs. Genes Dev. 2006 Nov 15;20(22):3174-84
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory