About   Help   FAQ
Hnrnpdtm1Rjsc
Targeted Allele Detail
Nomenclature
Symbol: Hnrnpdtm1Rjsc
Name: heterogeneous nuclear ribonucleoprotein D; targeted mutation 1, Robert J Schneider
MGI ID: MGI:3693617
Synonyms: Auf1-
Gene: Hnrnpd  Location: Chr5:99955935-99978938 bp, - strand  Genetic Position: Chr5, 48.46 cM, cytoband E3
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:116112
Parent Cell Line:  W4 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe 5' sequence of exon 3 was replaced with a neomycin resistance cassette. Immunoblot confirmed absence of protein in mutant spleen, thymus and testicle. (J:116112)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hnrnpd Mutation:  12 strains or lines available
References
Original:  J:116112 Lu JY, et al., Endotoxic shock in AUF1 knockout mice mediated by failure to degrade proinflammatory cytokine mRNAs. Genes Dev. 2006 Nov 15;20(22):3174-84
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
03/21/2017
MGI 6.08
The Jackson Laboratory