About   Help   FAQ
Hand1tm1(tTA)Prri
Targeted Allele Detail
Nomenclature
Symbol: Hand1tm1(tTA)Prri
Name: heart and neural crest derivatives expressed 1; targeted mutation 1, Paul R Riley
MGI ID: MGI:3693329
Gene: Hand1  Location: Chr11:57828713-57832147 bp, - strand  Genetic Position: Chr11, 35.27 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:116090
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129/Sv
Mutation
description
Allele Type:    Targeted (Transactivator)
Mutation:    Insertion
 
Mutation detailsThe tTA transactivator was inserted into the locus with a floxed neo cassette. The tTA transactivator is epxressed in an equivalent spatial pattern to endogenous Hand1. (J:116090)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hand1 Mutation:  3 strains or lines available
References
Original:  J:116090 Risebro CA, et al., Hand1 regulates cardiomyocyte proliferation versus differentiation in the developing heart. Development. 2006 Nov;133(22):4595-606
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
08/06/2019
MGI 6.14
The Jackson Laboratory