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Pawrtm1Lht
Targeted Allele Detail
Nomenclature
Symbol: Pawrtm1Lht
Name: PRKC, apoptosis, WT1, regulator; targeted mutation 1, Li-Huei Tsai
MGI ID: MGI:3692443
Synonyms: Par-4deltaLZ
Gene: Pawr  Location: Chr10:108332121-108414240 bp, + strand  Genetic Position: Chr10, 56.43 cM, cytoband D1
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:115199
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Disruption caused by insertion of vector
 
Mutation detailsExons 4 and 5 were removed by homologous recombination and resulted in a truncated protein lacking expression of the C-terminal leucine zipper region. (J:115199)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pawr Mutation:  14 strains or lines available
References
Original:  J:115199 Park SK, et al., Par-4 links dopamine signaling and depression. Cell. 2005 Jul 29;122(2):275-87
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
03/31/2020
MGI 6.15
The Jackson Laboratory