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Ptf1atm2.1Mgn
Targeted Allele Detail
Nomenclature
Symbol: Ptf1atm2.1Mgn
Name: pancreas specific transcription factor, 1a; targeted mutation 2.1, Mark A Magnuson
MGI ID: MGI:3691484
Synonyms: Ptf1aCitrine, Ptf1atm2Mgn, Ptf1aYFP
Gene: Ptf1a  Location: Chr2:19445663-19447501 bp, + strand  Genetic Position: Chr2, 13.37 cM, cytoband A2
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:115271
Parent Cell Line:  TL1/TL-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted
Mutation:    Insertion
 
Mutation detailsThis allele expresses citrine under the control of the endogenous promoter. Exons 1 and 2 were replaced by the citrine yellow variant of GFP inserted into exon 1, exon 2 and an frt-flanked hygro cassette via RMCE using the loxed cassette acceptor (LCA) allele-containing ES cells. (J:115271, J:135698)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ptf1a Mutation:  18 strains or lines available
References
Original:  J:115271 Fujitani Y, et al., Ptf1a determines horizontal and amacrine cell fates during mouse retinal development. Development. 2006 Nov;133(22):4439-50
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
03/02/2021
MGI 6.16
The Jackson Laboratory