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Targeted Allele Detail
Symbol: Taldo1tm1Perl
Name: transaldolase 1; targeted mutation 1, Andras Perl
MGI ID: MGI:3690444
Synonyms: TAL-
Gene: Taldo1  Location: Chr7:141392199-141402968 bp, + strand  Genetic Position: Chr7, 86.73 cM, cytoband F3-F4
Germline Transmission:  Earliest citation of germline transmission: J:114691
Parent Cell Line:  TC1/TC-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsA neomycin resistance gene replaced sequence spanning from exon 4 to intron 4, encoding amino acids 138-153. Western blot confirmed that wild-type protein was not detected in mutants. (J:114691)
View phenotypes and curated references for all genotypes (concatenated display).
In Structures Affected by this Mutation: 2 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Taldo1 Mutation:  6 strains or lines available
Original:  J:114691 Perl A, et al., Transaldolase is essential for maintenance of the mitochondrial transmembrane potential and fertility of spermatozoa. Proc Natl Acad Sci U S A. 2006 Oct 3;103(40):14813-8
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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MGI 6.16
The Jackson Laboratory