About   Help   FAQ
Egln1tm1Fong
Targeted Allele Detail
Nomenclature
Symbol: Egln1tm1Fong
Name: egl-9 family hypoxia-inducible factor 1; targeted mutation 1, Guo-Hua Fong
MGI ID: MGI:3690045
Synonyms: Phd2-
Gene: Egln1  Location: Chr8:124908596-124949254 bp, - strand  Genetic Position: Chr8, 72.86 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:114669
Parent Cell Line:  G4 (ES Cell)
Strain of Origin:  (129S6/SvEvTac x C57BL/6NCrl)F1
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExon 2 removed via cre mediated recombination. A neo remained downstream of the deleted sequence. RT-PCR confirmed absence of wild-type transcript. (J:114669)
Phenotypes
Loading...
View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Egln1 Mutation:  3 strains or lines available
References
Original:  J:114669 Takeda K, et al., Placental but Not Heart Defects Are Associated with Elevated Hypoxia-Inducible Factor {alpha} Levels in Mice Lacking Prolyl Hydroxylase Domain Protein 2. Mol Cell Biol. 2006 Nov;26(22):8336-46
All:  7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
07/21/2015
MGI 5.22
The Jackson Laboratory