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bpck
Spontaneous Allele Detail
Nomenclature
Symbol: bpck
Name: bilateral polycystic kidney deletion region; bilateral polycystic kidneys
MGI ID: MGI:3688712
Synonyms: Tmem67bpck
Gene: bpck  Location: unknown  Genetic Position: Chr4, Syntenic
Mutation
origin
Strain of Origin:  B6C3Fe a/a-tip/J
Mutation
description
Allele Type:    Spontaneous
Mutation:    Intergenic deletion
  bpck involves 12 genes/genome features (Gm26895, Cdh17, Gm22477 ...) View all
 
Mutation detailsThis spontaneous deletion spans approximately 0.6 cM between D4Mit261 and D4Mit19, including the coding region of 6 genes, but the bilateral polycystic kidney phenotype was traced specifically to the absence of Tmem67 via BAC rescue with various length BACs. (J:144929)
Inheritance:    Recessive
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 7 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any bpck Mutation:  1 strain or line available
References
Original:  J:144929 Cook SA, et al., A Mouse Model for Meckel Syndrome Type 3. J Am Soc Nephrol. 2009 Apr;20(4):753-64
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
04/13/2021
MGI 6.16
The Jackson Laboratory