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Pdcd1lg2tm1Shr
Targeted Allele Detail
Nomenclature
Symbol: Pdcd1lg2tm1Shr
Name: programmed cell death 1 ligand 2; targeted mutation 1, Arlene H Sharpe
MGI ID: MGI:3688152
Synonyms: PD-L2-
Gene: Pdcd1lg2  Location: Chr19:29410919-29471157 bp, + strand  Genetic Position: Chr19, 23.93 cM, cytoband C2-C3
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:113851
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    A targeting vector replaced the IgV exon with the hygromycin resistance gene. (J:113851)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Pdcd1lg2 Mutation:  7 strains or lines available
References
Original:  J:113851 Liang SC, et al., PD-L1 and PD-L2 have distinct roles in regulating host immunity to cutaneous leishmaniasis. Eur J Immunol. 2006 Jan;36(1):58-64
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/26/2014
MGI 5.19
The Jackson Laboratory