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Nlgn2tm1Bros
Targeted Allele Detail
Nomenclature
Symbol: Nlgn2tm1Bros
Name: neuroligin 2; targeted mutation 1, Nils Brose
MGI ID: MGI:3687639
Synonyms: NL2-
Gene: Nlgn2  Location: Chr11:69823122-69837784 bp, - strand  Genetic Position: Chr11, 42.89 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:113647
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA 380 bp fragment including the translation start site was replaced with a neo cassette via homologous recombination. Western blot confirmed absence of full length and truncated protein in whole brain homogenates from homozygous mice. (J:113647)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Nlgn2 Mutation:  7 strains or lines available
References
Original:  J:113647 Varoqueaux F, et al., Neuroligins determine synapse maturation and function. Neuron. 2006 Sep 21;51(6):741-54
All:  11 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory