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Bank1tm1Kuro
Targeted Allele Detail
Summary
Symbol: Bank1tm1Kuro
Name: B cell scaffold protein with ankyrin repeats 1; targeted mutation 1, Tomohiro Kurosaki
MGI ID: MGI:3686872
Gene: Bank1  Location: Chr3:135759124-136031827 bp, - strand  Genetic Position: Chr3, 63.04 cM
Alliance: Bank1tm1Kuro page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:113321
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsMost of exon 2 was replaced with a neomycin resistance gene in reverse orientation. Absence of protein was confirmed by Western blot of mutant spleen. (J:113321)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 3 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Bank1 Mutation:  57 strains or lines available
References
Original:  J:113321 Aiba Y, et al., BANK negatively regulates Akt activation and subsequent B cell responses. Immunity. 2006 Mar;24(3):259-68
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory