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Gbx2tm1Mrt
Targeted Allele Detail
Nomenclature
Symbol: Gbx2tm1Mrt
Name: gastrulation brain homeobox 2; targeted mutation 1, Gail R Martin
MGI ID: MGI:3665450
Synonyms: Gbx2flox
Gene: Gbx2  Location: Chr1:89927956-89931179 bp, - strand  Genetic Position: Chr1, 45.06 cM, cytoband C5-E1
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:42110
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsLoxP sites were inserted to flank exon 2, with a neo cassette upstream of the 5' loxP site. Aberrantly spliced transcripts were detected in these mutants. (J:42110)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gbx2 Mutation:  10 strains or lines available
References
Original:  J:42110 Wassarman KM, et al., Specification of the anterior hindbrain and establishment of a normal mid/hindbrain organizer is dependent on Gbx2 gene function. Development. 1997 Aug;124(15):2923-34
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory