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FgrMhdaali18
Chemically induced Allele Detail
Nomenclature
Symbol: FgrMhdaali18
Name: FGR proto-oncogene, Src family tyrosine kinase; Abnormal limb
MGI ID: MGI:3665439
Synonyms: Ali18
Gene: Fgr  Location: Chr4:132701406-132729204 bp, + strand  Genetic Position: Chr4, 66.11 cM
Morphologic appearance of feet and tail of FgrMhdaali18/FgrMhdaali18 and FgrMhdaali18/FgrMhdaali18+ mice.

Show the 3 phenotype image(s) involving this allele.

Mutation
origin
Strain of Origin:  C3HeB/FeJ
Mutation
description
Allele Type:    Chemically induced (ENU) (Not Specified)
Mutation:    Single point mutation
    ENU-mutagenesis induced a missense mutation in the C-terminal regulatory tail region. (J:266810)
Inheritance:    Semidominant
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 10 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Fgr Mutation:  124 strains or lines available
References
Original:  J:112868 Abe K, et al., New ENU-induced semidominant mutation, Ali18, causes inflammatory arthritis, dermatitis, and osteoporosis in the mouse. Mamm Genome. 2006 Sep;17(9):915-26
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
01/18/2022
MGI 6.17
The Jackson Laboratory