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Targeted Allele Detail
Symbol: Pdia3tm1Gjh
Name: protein disulfide isomerase associated 3; targeted mutation 1, Gunter J Hammerling
MGI ID: MGI:3664742
Synonyms: B-Erp57fl, ERp57flx
Gene: Pdia3  Location: Chr2:121413902-121438687 bp, + strand  Genetic Position: Chr2, 60.38 cM
Germline Transmission:  Earliest citation of germline transmission: J:112606
Parent Cell Line:  E14.1 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
    Exons 2 and 3 were flanked with loxP sites. Absence of protein was confirmed in immunoblot analysis. (J:112606)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Pdia3 Mutation:  9 strains or lines available
Original:  J:112606 Garbi N, et al., Impaired assembly of the major histocompatibility complex class I peptide-loading complex in mice deficient in the oxidoreductase ERp57. Nat Immunol. 2006 Jan;7(1):93-102
All:  8 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory