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Arpc3tm1Jtak
Targeted Allele Detail
Summary
Symbol: Arpc3tm1Jtak
Name: actin related protein 2/3 complex, subunit 3; targeted mutation 1, Junji Takeda
MGI ID: MGI:3664649
Synonyms: Arpc3KO
Gene: Arpc3  Location: Chr5:122529941-122544244 bp, + strand  Genetic Position: Chr5, 62.34 cM
Alliance: Arpc3tm1Jtak page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:111402
Parent Cell Line:  v6.5 (ES Cell)
Strain of Origin:  (C57BL/6 x 129S4/SvJae)F1
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    Exon 2 was replaced with a PGK-neo selection cassette via homologous recombination. (J:111402)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Arpc3 Mutation:  12 strains or lines available
References
Original:  J:111402 Yae K, et al., Sleeping beauty transposon-based phenotypic analysis of mice: lack of Arpc3 results in defective trophoblast outgrowth. Mol Cell Biol. 2006 Aug;26(16):6185-96
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory