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Serpina6tm1Tew
Targeted Allele Detail
Nomenclature
Symbol: Serpina6tm1Tew
Name: serine (or cysteine) peptidase inhibitor, clade A, member 6; targeted mutation 1, Thomas E Willnow
MGI ID: MGI:3664470
Synonyms: cbg-
Gene: Serpina6  Location: Chr12:103646630-103657212 bp, - strand  Genetic Position: Chr12, 52.98 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:112974
Parent Cell Line:  Other (see notes) (ES Cell)
Strain of Origin:  129/SvEmcTer
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    A neo replaced most of exon 2. Absence of protein was confirmed by Western blot analysis. (J:112974)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Serpina6 Mutation:  19 strains or lines available
Notes
ES cell line = ICp4
References
Original:  J:112974 Petersen HH, et al., Hyporesponsiveness to glucocorticoids in mice genetically deficient for the corticosteroid binding globulin. Mol Cell Biol. 2006 Oct;26(19):7236-45
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/12/2018
MGI 6.12
The Jackson Laboratory