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Nr1h3tm1Dgen
Targeted Allele Detail
Nomenclature
Symbol: Nr1h3tm1Dgen
Name: nuclear receptor subfamily 1, group H, member 3; targeted mutation 1, Deltagen
MGI ID: MGI:3664445
Synonyms: Lxra-
Gene: Nr1h3  Location: Chr2:91184061-91202834 bp, - strand  Genetic Position: Chr2, 50.52 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:112995
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Project Collection: Deltagen
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    A 42 bp fragment of exon 2 was replaced by a PGK-neo cassette. (J:112995)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nr1h3 Mutation:  18 strains or lines available
References
Original:  J:112995 Plosch T, et al., Abcg5/Abcg8-independent pathways contribute to hepatobiliary cholesterol secretion in mice. Am J Physiol Gastrointest Liver Physiol. 2006 Sep;291(3):G414-23
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/05/2017
MGI 6.11
The Jackson Laboratory