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H19tm7Tilg
Targeted Allele Detail
Nomenclature
Symbol: H19tm7Tilg
Name: H19, imprinted maternally expressed transcript; targeted mutation 7, Shirley M Tilghman
MGI ID: MGI:3663884
Synonyms: H19luc
Gene: H19  Location: Chr7:142575529-142578143 bp, - strand  Genetic Position: Chr7, 87.97 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:110857
Parent Cell Line:  E14.1TG3B1 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA targeting vector was designed to delete all but the first 3 nucleotides of the transcript and replace them with a gene encoding luciferase. A floxed neo was included in the vector. (J:110857)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any H19 Mutation:  5 strains or lines available
References
Original:  J:110857 Jones BK, et al., Igf2 imprinting does not require its own DNA methylation or H19 RNA. Genes Dev. 1998 Jul 15;12(14):2200-7
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/20/2017
MGI 6.10
The Jackson Laboratory