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Htttm5Szi
Targeted Allele Detail
Nomenclature
Symbol: Htttm5Szi
Name: huntingtin; targeted mutation 5, Scott Zeitlin
MGI ID: MGI:3663764
Gene: Htt  Location: Chr5:34761740-34912534 bp, + strand  Genetic Position: Chr5, 17.92 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:111323
Parent Cell Line:  W9.5/W95 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Disruption caused by insertion of vector
 
Mutation detailsA vector was designed to replace the promoter, exon 1 and part of intron 1 with a pgk-neo cassette. This allele is similar to Hdhtm1Szi except a pgk-neo cassette was used instead of a MC1-neo cassette. (J:111323)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Htt Mutation:  25 strains or lines available
References
Original:  J:111323 Dragatsis I, et al., A method for the generation of conditional gene repair mutations in mice. Nucleic Acids Res. 2001 Feb 1;29(3):E10
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory