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Ctcftm1Laat
Targeted Allele Detail
Nomenclature
Symbol: Ctcftm1Laat
Name: CCCTC-binding factor; targeted mutation 1, Wouter de Laat
MGI ID: MGI:3663291
Synonyms: Ctcff
Gene: Ctcf  Location: Chr8:105636568-105682922 bp, + strand  Genetic Position: Chr8, 53.04 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:112158
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA floxed neo cassette was inserted upstream of exon 3 and a floxed puromycin resistance cassette followed by a lacZ gene was inserted downstream of exon 12. (J:143271)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ctcf Mutation:  59 strains or lines available
References
Original:  J:112158 Splinter E, et al., CTCF mediates long-range chromatin looping and local histone modification in the beta-globin locus. Genes Dev. 2006 Sep 1;20(17):2349-54
All:  10 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
03/17/2015
MGI 5.21
The Jackson Laboratory