Ctcf^tm2Gal
Targeted Allele Detail

Summary

• Symbol: Ctcf^tm2Gal
• Name: CCCTC-binding factor; targeted mutation 2, Niels Galjart
• MGI ID: MGI:3663291
• Synonyms: Ctcf^f, Ctcf^tm1Laat
• Gene: Ctcf Location: Chr8:106363200-106409554 bp, + strand Genetic Position: Chr8, 53.04 cM
• Alliance: Ctcf^tm2Gal page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:112158
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A floxed neo cassette was inserted upstream of exon 3 and a floxed puromycin resistance cassette followed by a lacZ gene was inserted downstream of exon 12. (J:143271)

Expression

In Mice Carrying this Mutation:	8 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ctcf Mutation: 78 strains or lines available

References

• Original: J:112158 Splinter E, et al., CTCF mediates long-range chromatin looping and local histone modification in the beta-globin locus. Genes Dev. 2006 Sep 1;20(17):2349-54
• All: 34 reference(s)