Ptk6^tm1Aty
Targeted Allele Detail

Summary

• Symbol: Ptk6^tm1Aty
• Name: PTK6 protein tyrosine kinase 6; targeted mutation 1, Angela L Tyner
• MGI ID: MGI:3662667
• Gene: Ptk6 Location: Chr2:180836917-180845408 bp, - strand Genetic Position: Chr2, 103.62 cM
• Alliance: Ptk6^tm1Aty page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:110331
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The first exon and transcription start site were replaced with a pgk-neo cassette via homologous recombination. (J:110331)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ptk6 Mutation: 32 strains or lines available

References

• Original: J:110331 Haegebarth A, et al., Protein tyrosine kinase 6 negatively regulates growth and promotes enterocyte differentiation in the small intestine. Mol Cell Biol. 2006 Jul;26(13):4949-57
• All: 4 reference(s)