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Tg(H2-K-Cd86)27All
Transgene Detail
Nomenclature
Symbol: Tg(H2-K-Cd86)27All
Name: transgene insertion 27, James P Allison
MGI ID: MGI:3656476
Synonyms: B7.2mod transgenic, B7-2 Tg
Transgene: Tg(H2-K-Cd86)27All  Location: unknown  
Transgene
origin
Strain of Origin:  (C57BL/6J x CBA)F1
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Mutation detailsA construct in which Cd86 cDNA containing the coding region was placed under control of the H2-Kb promoter and immunoglobulin heavy chain enhancer was used to create the transgene. Line 27 expressed the transgene at moderate levels on B lymphocytes. (J:112475)
Phenotypes
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Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:112475 Fournier S, et al., T cell-mediated elimination of B7.2 transgenic B cells. Immunity. 1997 Mar;6(3):327-39
All:  4 reference(s)

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/12/2015
MGI 5.21
The Jackson Laboratory