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Nkx2-5tm4Rph
Targeted Allele Detail
Nomenclature
Symbol: Nkx2-5tm4Rph
Name: NK2 homeobox 5; targeted mutation 4, Richard P Harvey
MGI ID: MGI:3655239
Synonyms: Nkx2-5-, Nkx2-5GFP, Nkx2,5GFP
Gene: Nkx2-5  Location: Chr17:26838664-26841565 bp, - strand  Genetic Position: Chr17, 13.6 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:81343
Parent Cell Line:  W9.5/W95 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Expression
In Mice Carrying this Mutation: 26 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Nkx2-5 Mutation:  7 strains or lines available
References
Original:  J:81343 Biben C, et al., Cardiac septal and valvular dysmorphogenesis in mice heterozygous for mutations in the homeobox gene Nkx2-5. Circ Res. 2000 Nov 10;87(10):888-95
All:  10 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory