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Targeted Allele Detail
Symbol: Unc5btm1.1Dyl
Name: unc-5 netrin receptor B; targeted mutation 1.1, Dean Y Li
MGI ID: MGI:3654305
Gene: Unc5b  Location: Chr10:60762594-60831581 bp, - strand  Genetic Position: Chr10, 31.52 cM, cytoband B4
Germline Transmission:  Earliest citation of germline transmission: J:111275
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsExons 4 to 13 were flanked with loxP sites and an FRT-flanked neomycin resistance cassette was inserted upstream of exon 4. Cre-mediated recombination removed exons 4 through 13 and the selection cassette. RT-PCR analysis confirms the absence of transcript in homozygous mice. (J:111275)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Unc5b Mutation:  37 strains or lines available
Original:  J:111275 Wilson BD, et al., Netrins promote developmental and therapeutic angiogenesis. Science. 2006 Aug 4;313(5787):640-4
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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MGI 6.16
The Jackson Laboratory