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Nfkbiatm1Fey
Targeted Allele Detail
Nomenclature
Symbol: Nfkbiatm1Fey
Name: nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha; targeted mutation 1, Fiona E Yull
MGI ID: MGI:3654110
Synonyms: IkappaB-alpha-
Gene: Nfkbia  Location: Chr12:55489411-55492647 bp, - strand  Genetic Position: Chr12, 24.0 cM, cytoband C1-C3
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:110817
Parent Cell Line:  TL1/TL-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    A 300 bp region containing the promoter and part of exon 1 was replaced with a PGK-neo cassette. (J:110817)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nfkbia Mutation:  7 strains or lines available
References
Original:  J:110817 Chen CL, et al., Lymphocytes lacking I kappa B-alpha develop normally, but have selective defects in proliferation and function. J Immunol. 2000 Nov 15;165(10):5418-27
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory