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Oprd1tm2Kff
Targeted Allele Detail
Nomenclature
Symbol: Oprd1tm2Kff
Name: opioid receptor, delta 1; targeted mutation 2, Brigitte L Kieffer
MGI ID: MGI:3653589
Synonyms: DOReGFP, DORGFP
Gene: Oprd1  Location: Chr4:131838037-131871797 bp, - strand  Genetic Position: Chr4, 64.78 cM, cytoband D1-D3
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:111033
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S2/SvPas
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion
 
Mutation detailsHomologous recombination was used to introduce the EGFP cDNA into exon 3 in frame and upstream of the stop codon. Western blot demonstrated expression of an EGFP protein as expected. Quantitative mRNA analysis demonstrated that the insertion did not interrupt normal transcription of the locus. (J:111033)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Oprd1 Mutation:  21 strains or lines available
References
Original:  J:111033 Scherrer G, et al., Knockin mice expressing fluorescent delta-opioid receptors uncover G protein-coupled receptor dynamics in vivo. Proc Natl Acad Sci U S A. 2006 Jun 20;103(25):9691-6
All:  13 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/23/2021
MGI 6.17
The Jackson Laboratory