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Gnai3tm1Lbi
Targeted Allele Detail
Nomenclature
Symbol: Gnai3tm1Lbi
Name: guanine nucleotide binding protein (G protein), alpha inhibiting 3; targeted mutation 1, Lutz Birnbaumer
MGI ID: MGI:3652743
Gene: Gnai3  Location: Chr3:108107280-108146146 bp, - strand  Genetic Position: Chr3, 46.83 cM
Fusion of lumbar vertebrae in Gnai3tm1Lbi/Gnai3tm1Lbi mice

Show the 3 phenotype image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:194591
Parent Cell Line:  CCE/EK.CCE (ES Cell)
Strain of Origin:  129S/SvEv-Gpi1c
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    Part of intron 5 and exon 6 were replaced with a neo cassette. (J:68071, J:194591)
Inheritance:    Recessive
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Gnai3 Mutation:  21 strains or lines available
References
Original:  J:194591 Jiang M, et al., Mouse gene knockout and knockin strategies in application to alpha subunits of Gi/Go family of G proteins. Methods Enzymol. 2002;344:277-98
All:  24 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
03/14/2017
MGI 6.08
The Jackson Laboratory