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Igkctm1Bgmn
Targeted Allele Detail
Nomenclature
Symbol: Igkctm1Bgmn
Name: immunoglobulin kappa constant; targeted mutation 1, Marianne Bruggemann
MGI ID: MGI:3652576
Synonyms: Kappa-
Gene: Igkc  Location: Chr6:70726435-70726754 bp, + strand  Genetic Position: Chr6, 32.04 cM, cytoband C
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:28868
Parent Cell Line:  HM-1 (ES Cell)
Strain of Origin:  129P2/OlaHsd-Hprtb-m3
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
    A neomycin resistance gene was inserted into the gene by homologous recombination. (J:28868)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Igkc Mutation:  3 strains or lines available
References
Original:  J:28868 Zou X, et al., Subtle differences in antibody responses and hypermutation of lambda light chains in mice with a disrupted chi constant region. Eur J Immunol. 1995 Aug;25(8):2154-62
All:  7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory