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Clocktm1.1Rep
Targeted Allele Detail
Nomenclature
Symbol: Clocktm1.1Rep
Name: circadian locomotor output cycles kaput; targeted mutation 1.1, Steven M Reppert
MGI ID: MGI:3652400
Synonyms: Clockdelta5-6, Clocktm1.1Drw
Gene: Clock  Location: Chr5:76209868-76304792 bp, - strand  Genetic Position: Chr5, 40.63 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:109634
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsCre mediated recombination resulted in the excision of exons 5 and 6. Immunohistochemistry confirmed absence of protein in mutants. (J:109634)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Clock Mutation:  58 strains or lines available
References
Original:  J:109634 Debruyne JP, et al., A clock shock: mouse CLOCK is not required for circadian oscillator function. Neuron. 2006 May 4;50(3):465-77
All:  15 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory