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Xrcc4tm2.1Fwa
Targeted Allele Detail
Nomenclature
Symbol: Xrcc4tm2.1Fwa
Name: X-ray repair complementing defective repair in Chinese hamster cells 4; targeted mutation 2.1, Frederick W Alt
MGI ID: MGI:3641470
Synonyms: X-
Gene: Xrcc4  Location: Chr13:89848914-90089608 bp, - strand  Genetic Position: Chr13, 45.5 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:109585
Parent Cell Line:  TC1/TC-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
    Transient expression of cre recombinase removed exon 3 in ES cells. (J:109585)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Xrcc4 Mutation:  10 strains or lines available
References
Original:  J:109585 Yan CT, et al., XRCC4 suppresses medulloblastomas with recurrent translocations in p53-deficient mice. Proc Natl Acad Sci U S A. 2006 May 9;103(19):7378-83
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/05/2019
MGI 6.14
The Jackson Laboratory