Pdgfrb^tm2Msas
Targeted Allele Detail

Summary

• Symbol: Pdgfrb^tm2Msas
• Name: platelet derived growth factor receptor, beta polypeptide; targeted mutation 2, Masakiyo Sasahara
• MGI ID: MGI:3641437
• Synonyms: PDGFR-B^flox2000
• Gene: Pdgfrb Location: Chr18:61178222-61218133 bp, + strand Genetic Position: Chr18, 34.41 cM
• Alliance: Pdgfrb^tm2Msas page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:110616
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A 5.5 kb region containing exons 4-7 including the signal peptide-encoding region was flanked by loxP sites. (J:110616)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pdgfrb Mutation: 84 strains or lines available

References

• Original: J:110616 Ishii Y, et al., Mouse brains deficient in neuronal PDGF receptor-beta develop normally but are vulnerable to injury. J Neurochem. 2006 Jul;98(2):588-600
• All: 2 reference(s)