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Targeted Allele Detail
Symbol: Plxna1tm1Kik
Name: plexin A1; targeted mutation 1, Hitoshi Kikutani
MGI ID: MGI:3641211
Synonyms: plexin-A1-
Gene: Plxna1  Location: Chr6:89316314-89362620 bp, - strand  Genetic Position: Chr6, 39.91 cM, cytoband E2
Germline Transmission:  Earliest citation of germline transmission: J:110786
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsA 3 Kb fragment containing the second exon with the intitiation codon and the third exon with the coding sequence of the Sema-domain was replaced with a neo cassette. Deletion was confirmed by northern blotting an RT-PCR. (J:110786)
View phenotypes for all genotypes (concatenated display).
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Plxna1 Mutation:  25 strains or lines available
Original:  J:110786 Takegahara N, et al., Plexin-A1 and its interaction with DAP12 in immune responses and bone homeostasis. Nat Cell Biol. 2006 Jun;8(6):615-22
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.03
The Jackson Laboratory