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Dlk1tm1Hsul
Targeted Allele Detail
Nomenclature
Symbol: Dlk1tm1Hsul
Name: delta-like 1 homolog (Drosophila); targeted mutation 1, Hei Sook Sul
MGI ID: MGI:3640339
Synonyms: Pref-1-
Gene: Dlk1  Location: Chr12:109452823-109463336 bp, + strand  Genetic Position: Chr12, 60.17 cM, cytoband E-F1
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:77909
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA neomycin resistance gene was inserted into exons 2 and 3. Western blot analysis of mutants failed to detect the multiple alternative splice products found in wild-type mice. (J:77909)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Dlk1 Mutation:  13 strains or lines available
References
Original:  J:77909 Moon YS, et al., Mice lacking paternally expressed Pref-1/Dlk1 display growth retardation and accelerated adiposity. Mol Cell Biol. 2002 Aug;22(15):5585-92
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/20/2017
MGI 6.10
The Jackson Laboratory