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Sept5tm1Bld
Targeted Allele Detail
Nomenclature
Symbol: Sept5tm1Bld
Name: septin 5; targeted mutation 1, Antonio Baldini
MGI ID: MGI:3640090
Synonyms: Cdcrel1-, Cdcrel1tm1Bld
Gene: Sept5  Location: Chr16:18621811-18629938 bp, - strand  Genetic Position: Chr16, 11.53 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:67409
Parent Cell Line:  AB2.2 (ES Cell)
Strain of Origin:  129S7/SvEvBrd-Hprtb-m2
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExons 2-4 of Sept5 were replaced with an Hprt3' chromosome engineering cassette in a targeting vector. AB2.2 embryonic stem cells that were double-targeted in trans were used to create knockout mice. (J:67409)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Sept5 Mutation:  15 strains or lines available
References
Original:  J:67409 Lindsay EA, et al., Tbx1 haploinsufficiency in the DiGeorge syndrome region causes aortic arch defects in mice. Nature. 2001 Mar 1;410(6824):97-101
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
03/21/2017
MGI 6.08
The Jackson Laboratory