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Tg(Mef2c-cre)2Blk
Transgene Detail
Nomenclature
Symbol: Tg(Mef2c-cre)2Blk
Name: transgene insertion 2, Brian L Black
MGI ID: MGI:3639735
Synonyms: AHF-Cre, Mef2c-AHFCre, mef2c-AHF-Cre line 200A
Transgene: Tg(Mef2c-cre)2Blk  Location: unknown  
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Mutation detailsThe Mef2c anterior heart field enhancer and promoter (AHF) was cloned into a cre expression plasmid with the cre cDNA and the SV40 splice sequence and the polyA signal sequence. The Mef2c-AHF-Cre fragment was injected into male pronuclei of fertilized oocytes. Three founder lines were initially characterized and line 200A was used for further analysis. (J:103545)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Mef2c     Summary of all recombinase alleles driven by Mef2c.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:103545 Verzi MP, et al., The right ventricle, outflow tract, and ventricular septum comprise a restricted expression domain within the secondary/anterior heart field. Dev Biol. 2005 Nov 1;287(1):134-45
All:  52 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/26/2019
MGI 6.14
The Jackson Laboratory