About   Help   FAQ
Cpt1ctm1Mdln
Targeted Allele Detail
Nomenclature
Symbol: Cpt1ctm1Mdln
Name: carnitine palmitoyltransferase 1c; targeted mutation 1, M Daniel Lane
MGI ID: MGI:3639356
Gene: Cpt1c  Location: Chr7:44959372-44974851 bp, - strand  Genetic Position: Chr7, 29.07 cM, cytoband B2
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:109455
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA targeting vector was designed to replace exons 1 and 2, encoding the transcription initiation site and the first transmembrane domain of the protein, with a neomycin resistance cassette. Western blot failed to detect protein in mutant brains. (J:109455)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cpt1c Mutation:  25 strains or lines available
References
Original:  J:109455 Wolfgang MJ, et al., The brain-specific carnitine palmitoyltransferase-1c regulates energy homeostasis. Proc Natl Acad Sci U S A. 2006 May 9;103(19):7282-7
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
04/18/2017
MGI 6.08
The Jackson Laboratory