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Phf21atm1Tba
Targeted Allele Detail
Nomenclature
Symbol: Phf21atm1Tba
Name: PHD finger protein 21A; targeted mutation 1, Tadashi Baba
MGI ID: MGI:3629054
Synonyms: Bhc80-
Gene: Phf21a  Location: Chr2:92184106-92361835 bp, + strand  Genetic Position: Chr2, 50.8 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:109077
Parent Cell Line:  D3 (ES Cell)
Strain of Origin:  129S2/SvPas
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA targeting vector was designed to replace part of the seventh exon with a neomycin resistance cassette. The deleted sequence encoded a Gln-rich domain. RT-PCR and Western blot failed to detect transcript or protein, respectively, in mutants. (J:109077)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Phf21a Mutation:  170 strains or lines available
References
Original:  J:109077 Iwase S, et al., A component of BRAF-HDAC complex, BHC80, is required for neonatal survival in mice. FEBS Lett. 2006 May 29;580(13):3129-35
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/05/2017
MGI 6.11
The Jackson Laboratory