Cxcr4^tm2Tng
Targeted Allele Detail

Summary

• Symbol: Cxcr4^tm2Tng
• Name: C-X-C motif chemokine receptor 4; targeted mutation 2, Takashi Nagasawa
• MGI ID: MGI:3628644
• Synonyms: Cxcr4^flox, Cxcr4^loxP
• Gene: Cxcr4 Location: Chr1:128515936-128520030 bp, - strand Genetic Position: Chr1, 56.43 cM
• Alliance: Cxcr4^tm2Tng page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:109147
• Parent Cell Line: E14.1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• A targeting vector was designed to flank exon 2 with loxP sites. (J:109147)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Cxcr4 Mutation: 40 strains or lines available

References

• Original: J:109147 Tokoyoda K, et al., Cellular niches controlling B lymphocyte behavior within bone marrow during development. Immunity. 2004 Jun;20(6):707-18
• All: 19 reference(s)