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Cxcr4tm2Tng
Targeted Allele Detail
Nomenclature
Symbol: Cxcr4tm2Tng
Name: chemokine (C-X-C motif) receptor 4; targeted mutation 2, Takashi Nagasawa
MGI ID: MGI:3628644
Synonyms: Cxcr4flox, Cxcr4loxP
Gene: Cxcr4  Location: Chr1:128515936-128520030 bp, - strand  Genetic Position: Chr1, 56.43 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:109147
Parent Cell Line:  E14.1 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
    A targeting vector was designed to flank exon 2 with loxP sites. (J:109147)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 3 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Cxcr4 Mutation:  32 strains or lines available
References
Original:  J:109147 Tokoyoda K, et al., Cellular niches controlling B lymphocyte behavior within bone marrow during development. Immunity. 2004 Jun;20(6):707-18
All:  19 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/27/2022
MGI 6.21
The Jackson Laboratory