Tg(CAG-STC2)L314Gdm
Transgene Detail

Summary

• Symbol: Tg(CAG-STC2)L314Gdm
• Name: transgene insertion L314, Gabriel E DiMattia
• MGI ID: MGI:3626089
• Synonyms: Tg(ACTB-STC2)L314Gdm, Tg(CAG-STC2)L314Gdm
• Transgene: Tg(CAG-STC2)L314Gdm Location: unknown
• Alliance: Tg(CAG-STC2)L314Gdm page

Transgene origin

• Strain of Origin: C57BL/6 x CBA

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(CAG-STC2)L314Gdm expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  STC2 (8614)

  Stc2	(MGI:1316731)

• Mutation details: A promoter consisting of the cytomegalovirus IE enhancer fused to the chicken beta-actin promoter together with 5'UTR sequence and intron 1 of the chicken beta-actin was used to drive a 1247 bp human cDNA followed by the rabbit globin 3'UTR. Two independent lines were produced, L314 and L372. (J:96043)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:96043 Gagliardi AD, et al., Human stanniocalcin-2 exhibits potent growth-suppressive properties in transgenic mice independently of growth hormone and IGFs. Am J Physiol Endocrinol Metab. 2005 Jan;288(1):E92-105
• All: 1 reference(s)