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Targeted Allele Detail
Symbol: Cd248tm1Huso
Name: CD248 antigen, endosialin; targeted mutation 1, David L Huso
MGI ID: MGI:3625491
Gene: Cd248  Location: Chr19:5068078-5070637 bp, + strand  Genetic Position: Chr19, 4.24 cM
Germline Transmission:  Earliest citation of germline transmission: J:107172
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129/SvEv
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsA neomycin resistance gene replaced most of the single coding exon of the locus. RT-PCR confirmed absence of transcript in mutant colon, liver and skin samples. (J:107172)
View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cd248 Mutation:  14 strains or lines available
Original:  J:107172 Nanda A, et al., Tumor endothelial marker 1 (Tem1) functions in the growth and progression of abdominal tumors. Proc Natl Acad Sci U S A. 2006 Feb 28;103(9):3351-6
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.11
The Jackson Laboratory