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Targeted Allele Detail
Symbol: Dppa5atm1Yam
Name: developmental pluripotency associated 5A; targeted mutation 1, Shinya Yamanaka
MGI ID: MGI:3625479
Synonyms: Esg1-
Gene: Dppa5a  Location: Chr9:78367052-78368177 bp, - strand  Genetic Position: Chr9, 43.65 cM
Germline Transmission:  Earliest citation of germline transmission: J:107238
Parent Cell Line:  RF8 (ES Cell)
Strain of Origin:  129S4/SvJae
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsHomologous recombination was used to replace the entire coding sequence with either a vector containing an IRES-Betageo cassette or an IRES-HygR cassette constructed by a previous promoter trap selection in a BAC. Northern blot and Western blot confirmed absence of transcript and protein, respectively, in mutant ES cells. (J:107238)
View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Dppa5a Mutation:  15 strains or lines available
Original:  J:107238 Amano H, et al., Identification and targeted disruption of the mouse gene encoding ESG1 (PH34/ECAT2/DPPA5). BMC Dev Biol. 2006;6:11
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.11
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