Hpgds^tm1Urad
Targeted Allele Detail

Summary

• Symbol: Hpgds^tm1Urad
• Name: hematopoietic prostaglandin D synthase; targeted mutation 1, Yoshihiro Urade
• MGI ID: MGI:3623744
• Synonyms: hPGD2S^-, H-Pgds^-, HPGDS^-, Hpgds^tm1Groy, Hpgds^tm1Hjl
• Gene: Hpgds Location: Chr6:65094277-65121892 bp, - strand Genetic Position: Chr6, 30.11 cM, cytoband D-E
• Alliance: Hpgds^tm1Urad page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:171879
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Exon 2 was replaced by a neomycin resistance gene. (J:108359)

Expression

In Mice Carrying this Mutation:	6 assay results 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hpgds Mutation: 13 strains or lines available

References

• Original: J:171879 Mohri I, et al., Hematopoietic prostaglandin D synthase is expressed in microglia in the developing postnatal mouse brain. Glia. 2003 May;42(3):263-74
• All: 29 reference(s)