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Kmt2btm1.2Afst
Targeted Allele Detail
Nomenclature
Symbol: Kmt2btm1.2Afst
Name: lysine (K)-specific methyltransferase 2B; targeted mutation 1.2, A Francis Stewart
MGI ID: MGI:3623312
Synonyms: Mll2 FC
Gene: Kmt2b  Location: Chr7:30568858-30588726 bp, - strand  Genetic Position: Chr7, 18.63 cM, cytoband A3
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:107403
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
    Exon 2 was removed by cre recombination causing a frameshift in the transcript. (J:107403)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Kmt2b Mutation:  29 strains or lines available
References
Original:  J:107403 Glaser S, et al., Multiple epigenetic maintenance factors implicated by the loss of Mll2 in mouse development. Development. 2006 Apr;133(8):1423-32
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/08/2017
MGI 6.10
The Jackson Laboratory