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Il1rl1tm1Aki
Targeted Allele Detail
Nomenclature
Symbol: Il1rl1tm1Aki
Name: interleukin 1 receptor-like 1; targeted mutation 1, Shizuo Akira
MGI ID: MGI:3623124
Synonyms: ST2-, T1/ST2-
Gene: Il1rl1  Location: Chr1:40429570-40465415 bp, + strand  Genetic Position: Chr1, 19.19 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:58499
Parent Cell Line:  E14.1 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA targeting vector was designed to replace a 1280 base pair fragment encompassing exons 1 and 2, which encode amino acids 1-96 of the protein, with a neomycin resistance cassette. RT-PCR confirmed absence of transcript in mutants. (J:58499)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Il1rl1 Mutation:  22 strains or lines available
References
Original:  J:58499 Hoshino K, et al., The absence of interleukin 1 receptor-related T1/ST2 does not affect T helper cell type 2 development and its effector function. J Exp Med. 1999 Nov 15;190(10):1541-8
All:  9 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/27/2016
MGI 6.05
The Jackson Laboratory