About   Help   FAQ
Targeted Allele Detail
Symbol: Hellstm1Rarc
Name: helicase, lymphoid specific; targeted mutation 1, Robert J Arceci
MGI ID: MGI:3622321
Synonyms: Pasg-
Gene: Hells  Location: Chr19:38930990-38970470 bp, + strand  Genetic Position: Chr19, 33.57 cM, cytoband C3-D1
Germline Transmission:  Earliest citation of germline transmission: J:107145
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129X1/SvJ
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsExons 10-12, which encode the conserved helicase domains II through IV, were replaced with a neomycin resistance gene. A short transcript was detected by Northern blot, but Western blot detected no protein resulting from that transcript. (J:107145)
View phenotypes and curated references for all genotypes (concatenated display).
In Structures Affected by this Mutation: 21 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hells Mutation:  17 strains or lines available
Original:  J:107145 Sun LQ, et al., Growth retardation and premature aging phenotypes in mice with disruption of the SNF2-like gene, PASG. Genes Dev. 2004 May 1;18(9):1035-46
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
MGI 6.14
The Jackson Laboratory