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Hellstm1Rarc
Targeted Allele Detail
Nomenclature
Symbol: Hellstm1Rarc
Name: helicase, lymphoid specific; targeted mutation 1, Robert J Arceci
MGI ID: MGI:3622321
Synonyms: Pasg-
Gene: Hells  Location: Chr19:38930915-38971051 bp, + strand  Genetic Position: Chr19, 33.57 cM, cytoband C3-D1
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:107145
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129X1/SvJ
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExons 10-12, which encode the conserved helicase domains II through IV, were replaced with a neomycin resistance gene. A short transcript was detected by Northern blot, but Western blot detected no protein resulting from that transcript. (J:107145)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hells Mutation:  45 strains or lines available
References
Original:  J:107145 Sun LQ, et al., Growth retardation and premature aging phenotypes in mice with disruption of the SNF2-like gene, PASG. Genes Dev. 2004 May 1;18(9):1035-46
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/14/2017
MGI 6.11
The Jackson Laboratory